Disclaimer: This blog post is for informational purposes only and does not constitute medical advice. Please consult with your healthcare provider before making any decisions about your treatment.
If you have struggled with depression that hasn’t responded to traditional antidepressants, you might be dealing with treatment-resistant depression (TRD). SPRAVATO® (esketamine) nasal spray, recently approved as a monotherapy for TRD, offers a new approach to treatment.
How SPRAVATO® Works
SPRAVATO® is derived from ketamine but is specifically designed for use in depression. It works differently than typical antidepressants, which usually focus on increasing levels of certain brain chemicals like serotonin. Instead, SPRAVATO® primarily targets a receptor called NMDA (N-methyl-D-aspartate). This receptor is involved in learning, memory, and the brain’s ability to change and adapt. By blocking the NMDA receptor, SPRAVATO® may help “reset” brain circuits related to depression, which could explain why some people experience improvements quickly.
Important Considerations
- SPRAVATO® is not a cure-all and may not work for everyone.
- The use of SPRAVATO® is not recommended during pregnancy or while breastfeeding due to potential harm to the baby. More research is needed to understand the effects of SPRAVATO® on pregnant women and infants.
- Potential side effects include sedation, dissociation, increased blood pressure, and bladder problems.
- Due to the potential for abuse, SPRAVATO® is only available through a restricted program and must be administered in a certified healthcare setting.
Is SPRAVATO® Right for You?
If you’re considering SPRAVATO® for TRD, it’s crucial to have a candid conversation with your doctor. They can assess your needs and help you understand if it’s a suitable option based on your medical history and individual circumstances.
Disclaimer: This blog post is intended for informational purposes only and does not constitute medical advice. Please consult with your healthcare provider before making any decisions about your treatment.